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A research team from Hannover Medical School, RWTH Aachen University, Technical University Darmstadt and the University of Twente has developed an additive manufacturing-based design framework for artificial lungs that uses triply periodic minimal surface (TPMS) membranes in place of conventional hollow fiber bundles.
Published in Advanced Materials, the study combines simulations, printable silicone materials and endothelialization to assess TPMS membranes for improving blood flow and oxygen transfer in biohybrid lungs.
Artificial lungs and extracorporeal membrane oxygenation (ECMO) systems currently rely largely on bundles of hollow poly(4-methyl-1-pentene) fibers. Blood flows around these fibers while oxygen-rich gas passes through their interiors.
This architecture can create uneven